منابع مشابه
Lipid metabolism in the newborn heart.
In recent years long chain fatty acids have been shown to be the principal metabolic fuel of the adult heart (1-3). For the tissues of the mammalian fetus, however, carbohydrates rather than lipids appear to serve as the primary source of energy (4, 5). This difference in energy metabolism related to maturation suggested that the heart of the newborn, in contrast to that of the adult, might be ...
متن کاملLipid metabolism in the fetus and the newborn.
During late gestation, although maternal adipose tissue lipolytic activity becomes enhanced, lipolytic products cross the placenta with difficulty. Under fasting conditions, free fatty acids (FFA) are used for ketogenesis by the mother, and ketone bodies are used as fuels and lipogenic substrates by the fetus. Maternal glycerol is preferentially used for glucose synthesis, saving other gluconeo...
متن کاملDefective lipid metabolism in the failing heart.
The metabolism of long chain fatty acids was investigated in the failing heart of guinea pigs with chronic constriction of the ascending aorta. Homogenates prepared form failing hearts exhibited (a) a decreased capacity to oxidize palmitic acid (failure = 0.50 +/- 0.06 mumole/g of protein per 20 min; control = 1.09 +/- 0.10); (b) a reduced level of carnitine, a myocardial constituent which serv...
متن کاملLipid metabolism in normoxic and ischemic heart.
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متن کاملThe Splenectomy Effects on Lipid Profile and Glucose Metabolism in the Major Thalassemia Patients
Background: Splenectomy is a common treatment for beta thalassemia. It not only eliminates many complications by reducing the need for blood transfusion, but also causes new complications that threaten the patientschr('39') health. The aim of this study was to determine if splenectomy could alter the lipid profile and glucose metabolism in beta thalassemia major patients. Methods: In this case-...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1965
ISSN: 0021-9738
DOI: 10.1172/jci105270